L-Kynurenine D4 -- 100 mg

The kynurenine pathway is a metabolic pathway leading to the production of nicotinamide adenine dinucleotide (NAD+) from the degradation of the essential amino acid tryptophan.

Kynurenine, Kynurenic acid , 3-Hydroxykynurenine, 3-Hydroxyanthranilic acid and Quinolinic acid are metabolites of the kynurenine pathway and available as deuterated standards from Buchem BV.

Publications:

Quantitative profiling of biomarkers related to B-vitamin status, tryptophan metabolism and inflammation in human plasma by liquid chromatography/tandem mass spectrometry.

http://www.ncbi.nlm.nih.gov/pubmed/19337982

A simple LC-MS/MS method for determination of kynurenine and tryptophan concentrations in human plasma from HIV-infected patients.

http://www.ncbi.nlm.nih.gov/pubmed/23742309

Plasma tryptophan, kynurenine and 3-hydroxykynurenine measurement using automated on-line solid-phase extraction HPLC–tandem mass spectrometry.

http://www.ncbi.nlm.nih.gov/pubmed/19196554